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From PyWiki

Python-Ogre is a Python wrapper for the Ogre3D library and many Ogre modules. You can use Python, a high-level, easy to learn, and powerful programming language, to write high quality 3D applications. No more malloc / pointers / compiling / headers etc :)

Advantages

• A lot less code required than with C++
• Less code -> fewer bugs
• More portable
• No compiling necessary
• You don't have to worry about memory allocation, long std::xyz instructions
• Code is more readable
• Easy to use in-game python console to access any function/variable in your code
• Easy to use event registration in CEGUI layout files -> bound directly to a python function

Disadvantages

• Heavy computations - Pure python is not very fast at straight number crunching (but it may be fast enough).
• Multithreading - Threads in python only execute one at a time, and thus do not take advantage of multiple cores or processors.
  • As of python 2.6: There is a standard library, multiprocessing, which will leverage multiple cores at the cost of an expanded memory footprint, and it is fairly easy to use.
• Memory footprint - Python and Python-Ogre do take a bit of memory, a few dozen megabytes. Not a big deal with modern machines, though

In-Between

• Fast code - if you need a lot of computation, (eg. for advanced pathfinding) you can make a C/C++ library and call its functions from within python